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Research insights and technical articles from GeneMedi.
More than 90% of adults carry Epstein-Barr virus (EBV) for life, yet rarely develop disease. But EBV is classified by the World Health Organization as a Group I carcinogen, associa...
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Early diagnosis of cutaneous T-cell lymphoma (CTCL) has long been a challenge for dermatologists. This is especially true for the most common type, mycosis fungoides (MF), whose ea...
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Chronic spontaneous urticaria (CSU) is a disease driven primarily by mast cells, manifesting as recurrent wheals, angioedema, or both. Approximately up to 1% of the global populati...
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The pathogenesis of asthma is far more complex than the phrase "airway inflammation" suggests. Type Ⅱ inflammation, eosinophils, cytokine networks… each link influences the directi...
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Solar ultraviolet radiation is the primary cause of skin cancer—this is already consensus. But a key question has long remained unresolved: after ultraviolet radiation causes melan...
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ALPK3 gene truncating mutations are an important genetic cause of hypertrophic cardiomyopathy, accounting for approximately 2% of cases. There is currently no curative treatment fo...
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A phase 1 trial in patients aged 12–18 years with severe hemophilia B has yielded an intriguing signal: factor IX activity peaks higher than in adults, but declines more markedly b...
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The combination of suprachoroidal injection and RPE-specific promoters is rewriting the rules of retinal gene delivery. Dry age-related macular degeneration (dAMD) is a leading cau...
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Hereditary cerebellar ataxias have long been regarded as a group of neurodegenerative diseases that are difficult to intervene in. When the causative gene encodes a secreted synapt...
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Sandhoff disease (SD) is caused by defects in the HEXA/HEXB genes, leading to Hex enzyme deficiency and accumulation of GM2 ganglioside in lysosomes. Previous studies mostly delive...
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